Emily Woodland

STAR Scholars Abstract

Drexel Dragon Heart: Next Generation Blood Pump Design for Pediatric Patients with Heart Failure

  • October 3, 2024 at 7:36 AM
  • Visible to group members and anyone with the link
The treatment of children with heart failure is a formidable challenge. Heart transplantation, when available, becomes the only lifesaving option. Children could benefit from a blood pump: a medical device designed to assist the ailing heart with pumping blood. Blood pumps for children, however, lag behind those for adults. While adult devices have been employed in children, the operation of these adult pumps off-design increases the risk of blood cell damage and clotting. Pediatric patients have limited options due to the anatomy of childhood heart disease and increased cardiovascular demands of physical growth. To address this unmet clinical need, we have innovated The Dragon Heart, which uniquely integrates multiple pediatric blood pumps. This compact device (60mm x 50mm) suspends the pumps in a magnetic field, thus facilitating a long operational lifespan and lower blood cell trauma. We performed high-quality modeling of two new pump designs, which produced target performance; 40-180 mmHg for 0.5-4 L/min at 2000- 3000 RPM. Internal fluid forces were below 2.5 N, and fluid stresses were at acceptable levels. This work serves as the foundation for the next phase of prototype benchtop testing, moving toward animal studies.